Measles in children


  • U.I. Marusik High State Educational Institution of Ukraine “Bukovynian State Medical University”, Chernivtsi, Ukraine,



measles, high contagiosity, vaccination, children


The article deals with the history of measles virus discovery, epidemic outbreak of measles over the last 15 years in Ukraine. The paper presents the data on the features of measles clinical picture in children and adults with typical and atypical forms, criteria for diagnosis, as well as possible protection against this dangerous infectious disease.


Kramariov SO, editor. Іnfekcіjnі hvorobi u dіtej [Infectious diseases in children]. Kyiv: Medicine; 2010. 392 p. (In Ukrainian).

Chudna LM. Epidemiological situation of measles in Ukraine for 2002-2006. In: Proceedings “Vcheniya L.V. Gromashevsky in the modern conditions of struggle against infectious diseases”. Kyiv; 2006. 133-8 p. (In Ukrainian).

Mojseyeva AV, Vasylyeva VA, Kondrashova NS. Measels infection and its prevention at the present stage. Perinatologіja і Pedіatrіja. 2009;4:68-71.

Malyi VP. Modern problems of the measles: clinical picture, diagnosis and treatment. Klіnіchna іmunologіja. alergologіja. Іnfektologіja.. 2012;1-2(50):10-7. (in Ukrainian).

Further Information on Vaccine Safety / Department of Vaccines and Biologicals. Geneva: WHO, 2008.

Moiseyeva GV. Impact of immune prophylaxis on the epidemic process of measles. Zdorov’ye Rebenka. 2010;3(24):89-92. (In Ukrainian).

Ajdaraliyeva Ch.X. Prospects for elimination of measles in Ukraine. SES. 2005;1:56.

Kramaryev SO, Yevtushenko VV, Vygovska OV. Measles in children: an actual issue of the present. Modern infections. 2009;3-4:82-6. (In Ukrainian).

Moiseyeva GV. Koncepcіja elіmіnacії koru v umovah Ukraїni [The concept of elimination of bark in Ukraine]. Kyiv; 2011. 36 p. (In Ukrainian).

Global measles and rubella strategic plans: 2012-2020. – Geneva: WHO; 2012. 44 p. Available from:

Patel MK, Gacic-Dobo M, Strebel PM, et al. Progress Toward Regional Measles Elimination – Worldwide 2000–2015. 2016;65(44):1228-33.

World health statistics. 2012. – Geneva: WHO; 2012. 180 p. Available from:

Kutsina DV, Rubtsova EI. Studying the dynamics of vaccine-preventable childhood infections in Transcarpathian region. Ukraina. Zdorov’ja Nacіi. 2017;2(43):57-61. (In Ukrainian).

Kramaryev SO, Vygovska OV, Shpak IV, et al. Contemporary course of measles in children. Pediatrician. 2013;3(24):26-31. (In Ukrainian).

Vygovska OV, Kramaryev SO, Shpak IV, et al. Kir in children. Clinical Immunology. Allergology. Infectology. 2013;4(63):12-9. (In Ukrainian).

Duru CO, Peterside O, Adeyemi OO. A 5 year review of childhood measles at the Niger Delta University Teaching Hospital, Bayelsa state, Nigeria. Journal of Medicine and Medical Sciences. 2014;5(4):78-86.

Shakeel A, Mukhtiar A, Sherbaz HK. Risk Factors Associated with Complicated Measles in Children. P J M H S. 2014;8(2):469-71. (In Dutch). PMID: 9555140.

Perry RT, Halsey NA. The clinical significance of measles: a review. J Intect Dis. 2004;189:4-16. PMID: 15106083. doi: 10.1086/377712.

Lagunju IA, Orimadegun AE, Oyedem DG. Measles in Ibadan: A continuous scourge. Afr J Med Sci. 2005;34(338):7-9. PMID: 16752670.

Polyak MA. Basic clinical and pathogenetic mechanisms of development of cow infection. Scientific Bulletin of Uzhgorod University, series "Medicine". 2013;1(46):37-40. (In Ukrainian).

Duda AK. Measles: "Baby" infections show themselves. Mistectvo lіkuvannja. 2011;9:34-8. (In Russian).

Kaspina AI, Drozhzhina VA, Bojchenko DG. Scarlet fever, measles, rubella. Their similarity and differences in clinical manifestations on the mucous membrane of the rotosynopharynx and skin. Institut stomatologii. 2005;26:88-9. (In Russian).

Kramaryev SO. Іnfekcіjnі hvorobi u dіtej (klіnіchnі lekcії) [Infectious diseases in children. Clinical lectures]. Kyiv: MORION; 2003. 479 p. (In Ukrainian).

Minina TD. Detskie infekcii. Vetrjanka, krasnuha, svinka, skarlatina, kokljush, kor' i drugie [Childhood infections: chickenpox, rubella, mumps, scarlet fever, pertussis, measles and others]. Saint-Petersburg: Ves’; 2005. 118 p. (In Russian).

Avota E, Gassert E, Schneider-Schaulies S. Measles virus-induced immunosuppression: from effectors to mechanisms. Med Microbiol Immunol. 2010;199(3):227-37. doi: 10.1007/s00430-010-0152-3.

Griffin DE, Lin WH, Pan CH. Measles virus, immune control, and persistence. FEMS Microbiol Rev. 2012.;36(3):649-62. doi: 10.1111/j.1574-6976.2012.00330.x.

Plemper RK, Brindley MA, Iorio RM. Structural and mechanistic studies of measles virus illuminate paramyxovirus entry. PLoS Pathog. 2011;7(6):e1002058. doi: 10.1371/journal.ppat.1002058.

de Vries RD, Mesman AW, Geijtenbeek TB, et al. The pathogenesis of measles. Curr Opin Virol. 2012;2(3):248-55. doi: 10.1016/j.coviro.2012.03.005.

Yanagi Y, Takeda M, Ohno S. Measles virus: cellular receptors, tropism and pathogenesis. J Gen Virol. 2006;87, pt. 10:2767-79. doi: 10.1099/vir.0.82221-0.