The analysis of association of polymorphism of IL-4, IL-10 and TNF cytokine genes with biochemical and immunological indicators in patients with chronic hepatitis C

E.N. Usychenko, E.M. Usychenko, Yu.I. Bazhora

Abstract


The article presents studies of the genetic profile (IL-4 (C589T), IL-10 (G1082A) and TNF-α (G308A)), clinical and biochemical indices in 100 patients with chronic hepatitis C living in the Odesa region. Possible markers of the severity of disease course and its prognosis were detected.

Keywords


chronic hepatitis C; disease progression; polymorphism of cytokine genes

References


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DOI: https://doi.org/10.22141/2312-413x.5.6.2017.122141

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