Dynamics of biochemical parameters and functional state of the autonomic nervous system in patients with acute hepatitis B with chronic alcohol use in hepatotoxic doses

E.A. Furyk, E.V. Ryabokon, T.E. Onishchenko, V.G. Savelyev, D.A. Zadiraka


It is shown that in patients with acute hepatitis B with chronic alcohol use in hepatotoxic doses, more significant functional disturbances of the autonomic nervous system state occur with the development of vegetative imbalance towards vagotonia, which persist in the period of convalescence.


acute hepatitis В; heart rate variability; alcohol


Gacche RN, Kaid AM. Epidemiology of viral hepatitis B and C infections in Ibb city, Yemen. Hepat Mon. 2012 Jul; 12(7):460-462. doi: 10.5812/hepatmon.6140.

Bozza C, Cinausero M, Iacono D, Puglisi F. Hepatitis B and cancer: A practical guide for the oncologist. Crit Rev Oncol Hematol. 2016 Feb;98:137-46. doi: 10.1016/j.critrevonc.2015.10.017.

Mina T, Amini Bavil Olyaee S, Tacke F, Maes P, Van Ranst M, Pourkarim MR. Genomic Diversity of Hepatitis B Virus Infection Associated With Fulminant Hepatitis B Development. Hepat Mon. 2015 Jun 23;15(6):e29477. doi: 10.5812/hepatmon.29477v2.

Sitnikov IG, Maleev VV, Shoshin AA. Optimization of hepatoprotective therapy of viral hepatitis with consideration of neuromediatory link of pathogenesis. Terapevticheskij arkhiv. 2006;78(11):12-17. (in Russian).

Van Laar JO, Peters CH, Vullings R, Houterman S, Oei SG. Power spectrum analysis of fetal heart rate variability at near term and post term gestation during active sleep and quiet sleep. Early Hum Dev. 2009 Dec;85(12):795-8. doi: 10.1016/j.earlhumdev.2009.11.001.

Voronenko JuV, Moskalenko VF, Procek OG, et al, authors. Voronenko JuV, Moskalenko VF, editors. Social'na medycyna ta organizacija ohorony zdorov’ja : Pidruchnyk [Social medicine and organization of health care: Textbook]. Ternopil: Ukrmedknyga; 2000. 680 pp. (in Ukrainian).

Heart rate variability: standard of measurement, physiological and clinical use. Task Forse of European Society of Cardiology and The North American Society of Pacing and Electrophysiology. Circulation. 1996 Mar 1;93(5):1043-65. PMID: 8598068.

Andrejchyn MA, Dryzhak VI, Rjabokon' OV, Kopcha VS, authors. Virusni gepatyty i rak pechinky [Viral Hepatitis and Liver Cancer]. Ternopil: TSMU; 2010. 188 c. (in Ukrainian).

Genovesi S, Prata Pizzala DM, Pozzi M, et al. Baroreceptor sensitivity and baroreceptor effectiveness index in cirrhosis: the relevance of hepatic venous pressure gradient. Liver Int. 2010 Feb;30(2):232-9. doi: 10.1111/j.1478-3231.2009.02125.x.

Lane JD, Adcock RA, Burnett RE. Respiratory sinus arrhythmia and cardiovascular responses to stress. Psychophysiology. 1992 Jul;29(4):461-70. PMID: 1410177.

Copyright (c) 2018 ACTUAL INFECTOLOGY

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.


© Publishing House Zaslavsky, 1997-2018


   Seo анализ сайта