DOI: https://doi.org/10.22141/2312-413x.8.2.2020.199733

The effectiveness of racecadotril in the treatment of rotavirus infection in children

I.I. Nezghoda, O.M. Naumenko, A.A. Asaulenko, O.S. Onofriichuk, L.M. Brovinska, A.M. Kolesnyk, O.V. Nikulchenko, N.I. Sinchuk

Abstract


The article deals with the effectiveness of the use of racecadotril preparation as a pathogenetic agent in the treatment of rotavirus infection in children. There were 40 patients under the age of 5 years with rotavirus infection under observation. All children underwent a set of general laboratory studies. To establish the etiological factor, immunochromatographic analysis was used to detect rotavirus antigen, and bacteriological examination of the feces — to study bacterial flora. Comprehensive treatment included basic therapy according to protocols. Children of the main group (n = 20) received the antisecretory drug racecadotril in an age-related dosage from the first day of inpatient treatment. The use of this drug has influenced the main clinical symptoms of rotavirus infection in children — accelerated the elimination of vomi­ting and normalization of the consistency of feces, and also allowed reducing the duration of diarrheal syndrome, which also allowed us to decrease the time of inpatient treatment in an infectious disease hospital.


Keywords


rotavirus infection; children; treatment; raceca­dotril; Hidrasec

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