Peculiarities of a humoral immune response in coronavirus infection (COVID-19)

Authors

  • O.M. Zinchuk Danylo Halytsky Lviv National Medical University, Lviv, Ukraine
  • A.V. Petrukh Diagnostic Center “MeDIS”, Lviv, Ukraine
  • N.I. Hrynchyshyn Diagnostic Center “MeDIS”, Lviv, Ukraine
  • К.К. Shvaievska Diagnostic Center “MeDIS”, Lviv, Ukraine

DOI:

https://doi.org/10.22141/2312-413X.9.1.2021.228825

Keywords:

coronavirus, COVID-19, immunoglobulin, enzyme-linked immunosorbent assay

Abstract

We reviewed scientific data published during the recent 12 months about peculiarities of a humoral immune response in coronavirus infection (COVID-19). We also examined the concentration of immunoglobulin G against SARS-CoV-2 in 65 people in the Diagnostic Center “MeDIS” in 2020 with the diagnostic titer of specific antibodies. We established that in 3 months after primary examination of serum 60 % of examined patients presented high titers of IgG against SARS-CoV-2 (seropositivity rate > 7) in ELISA test. The highest level of IgG against SARS-CoV-2 in 3 months after the primary examination was revealed in those with a high initial level of antibodies against this virus.

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Published

2021-04-22

Issue

Section

Original Researches