Spectrum of Antimicrobial Properties of Tinctures of Medical Plants
The article discusses the biological properties of herbal preparations, which are not widely used in practical medicine, that’s why their usage in purulent septic infections could not cause widespread resistance. The purpose of this work is to establish and to compare the spectrum of antimicrobial properties of tinctures of medical plants in order to form a reserve of new sources of antimicrobial agents, some of which can be extracted from plants. Screening of antimicrobial properties in vitro was carried out for 12 herbal tinctures on 15 test strains of microorganisms. There has been revealed the presence of antimicrobial properties in the tinctures of medical plants, most convincing results were observed in infusions of mountain arnica, Echinacea Purpurea and eucalyptus. As for the reference strains of microorganisms, the minimum inhibitory and minimum bactericidal concentration of which ranged from 1 : 128 to 1 : 3, the moderate activity ha been observed in tinctures of peppermint and Sophora Japanese with indicators from 1 : 32 to 1 : 8. In turn, spectrum of antimicrobial properties appeared to be broad to collection strains that was predictable, but the results obtained from researches of the impact on clinical strains of microorganisms, which are resistant to many antibiotics, deserve special attention. Thus, the antimicrobial activity of herbal tinctures reduced to one dilution for each type of sensitive species, and sometimes coincided, indicating the absence of resistance to these drugs and determining as uniformly sensitive ones the reference collection and clinical strains to plant extracts. The findings demonstrated that plant extracts are a potential reserve for the creation of new sources of antimicrobial agents, particularly in relation to antibiotic-resistant clinical strains of microorganisms that are formed under the constant influence of synthetic and semi-synthetic drugs.
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