Spectrum of Antimicrobial Properties of Tinctures of Medical Plants
The article discusses the biological properties of herbal preparations, which are not widely used in practical medicine, that’s why their usage in purulent septic infections could not cause widespread resistance. The purpose of this work is to establish and to compare the spectrum of antimicrobial properties of tinctures of medical plants in order to form a reserve of new sources of antimicrobial agents, some of which can be extracted from plants. Screening of antimicrobial properties in vitro was carried out for 12 herbal tinctures on 15 test strains of microorganisms. There has been revealed the presence of antimicrobial properties in the tinctures of medical plants, most convincing results were observed in infusions of mountain arnica, Echinacea Purpurea and eucalyptus. As for the reference strains of microorganisms, the minimum inhibitory and minimum bactericidal concentration of which ranged from 1 : 128 to 1 : 3, the moderate activity ha been observed in tinctures of peppermint and Sophora Japanese with indicators from 1 : 32 to 1 : 8. In turn, spectrum of antimicrobial properties appeared to be broad to collection strains that was predictable, but the results obtained from researches of the impact on clinical strains of microorganisms, which are resistant to many antibiotics, deserve special attention. Thus, the antimicrobial activity of herbal tinctures reduced to one dilution for each type of sensitive species, and sometimes coincided, indicating the absence of resistance to these drugs and determining as uniformly sensitive ones the reference collection and clinical strains to plant extracts. The findings demonstrated that plant extracts are a potential reserve for the creation of new sources of antimicrobial agents, particularly in relation to antibiotic-resistant clinical strains of microorganisms that are formed under the constant influence of synthetic and semi-synthetic drugs.
Abreu AC. [Plants as sources of new antimicrobials and resistance-modifying agents]. Natural Product Reports. 2012; 29: 1007-1021. English.
Churski K, Kaminski TS, Jakiela S. [Rapid screening of antibiotic toxicity in an automated microdroplet system]. Lab on a Chip. 2012; 9: 1629-1637. English.
Dante G, Facchinetti F. [Herbal treatments for alleviating premenstrual symptoms : a systematic review]. Journal of Psychosomatic Obstetrics & Gynecology. 2011;32(1) : 42-51. English.
Fernández L, Breidenstein EBM, Hancock REW. [Creeping baselines and adaptive resistance to antibiotics]. Drug resistance. 2011;14(1) : 1-21. English.
Garvey MI, Rahman MM, Gibbons S. [Medicinal plant extracts with efflux inhibitory activity against Gram-negative bacteria]. Journal of antimicrobial agents. 2011;37(2) : 145-151. English.
Halloran J. [The Overuse of Antibiotics in Food Animals Threatens Public Health]. Consumer union. Policy & action for consumer reports. 2012. English. Access mode : https : //consumersunion.org/news/the-overuse-of-antibiotics-in-food-animals- threatens-public-health-2/
Kemper Haarberg KM. [Nutraceutical efficacy in experimental animal models of inflammatory bowel disease : Echinacea angustifolia, Prunella vulgaris and Hypericum gentianoides]. Iowa State University. 2011;199р. English.
Leal CM, Cruz SM, Marroquín MN, Gaitán IC. [Antimicrobial activity of essential oils and ethanolic extracts of three species of laurel (Litsea spp.) from Guatemala]. Acta Horticulturae. 2014;1030 : 23-29. English.
Nathan C, Cars O. [Antibiotic Antibiotic Resistance — Problems, Progress, and Prospects]. The new England journal of medicine. 2014;371 : 1761-1763. English.
Palombo EA. [Traditional Medicinal Plant Extracts and Natural Products with Activity against Oral Bacteria : Potential Application in the Prevention and Treatment of Oral Diseases]. Evidence-Based Complementary and Alternative Medicine. 2011;2011 : 15. English.
Pierro D, Rapacioli F, Ferrara G. [Use of a standardized extract from Echinacea angustifolia (Polinacea[R]) for the prevention of respiratory tract infections]. Alternative Medicine Review. 2012;17 : 325. English.
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