To the Question about the Features of the Course of Enterohemorrhagic and Other Escherichia Coli Infections

N.V. Pronko, V.M. Tsyrkunov, T.V. Yakusevich


The article presents information about Escherichia coli infections, the outbreak of which was recorded in 2011 in Europe. In Hrodno region for 15 years of observations, there were registered 158 cases of Escherichia coli infection, the proportion of children up to 14 years was 83.5 % (132 cases). Preferential information refers to the enterohaemorrhagic Escherichia coli infection, which occur in severe form with the development of lethal complications in the form of hemolytic uremic syndrome and acute renal failure. The article provides guidelines on the clinical and laboratorial diagnosis, treatment of enterohaemorrhagic Escherichia coli infection complicated by hemolytic uremic syndrome, prevention.


Escherichia coli infection; enterohaemorrhagic Escherichia coli infection; hemolytic uremic syndrome


Ershova IB, Mochalova AA, Osipova TF, Reshchikov VA, Kozina SYu. [Drugs reducing microbiocenosis as the causal treatment of acute intestinal infections in children]. Aktual'naya infektologiya. 2015;7(2):45-50. Russian

Pokrovskiy VI, Pak SG, Briko NI, Danilkin BK. [Infectious diseases and epidemiology: Tutorial]. M.: GEOTAR-MED, 2004. – 816 s. Russian.

On peculiarities of the appointment of antibacterial drugs for infections caused by E. coli O104: H4 [Pismo Ministerstva Zdravoohraneniya Respubliki Belarus]. 2011. № 02-2-04/1783. Russian.

Pronko NV, Danilevich NA, Konyuk LA. [Epidemiological and clinical features of the syndrome of acute diarrhea in children]. Journal of Grodno State Medical University. 2014;(3):92-95. Russian.

Bea WK, Lee YK, Cho MS. et al. A case of hemolytic uremic syndrome caused by Escherichia coli 104:H4. Yonsei Med. J. 2006;47(3):437-439.

Lu HJ, Breidt FJr, Pérez-Díaz IM, Osborne JA. Antimicrobial effects of weak acids on the survival of Escherichia coli O157:H7 under anaerobic conditions. J Food Prot. 2011;74(6):893-898.

O'Reilly KM, Low JC, Denwood MJ. et al. Associations between the presence of virulence determinants and the epidemiology and ecology of zoonotic Escherichia coli. Appl Environ Microbiol. 2010;76(24):8110-8116.

Zhou Z, Li X, Liu B, et al. Derivation of Escherichia coli O157:H7 from its O55:H7 precursor. PLoS One. 2010;5(1):8700-8705.

Poolpol K, Gadner B, Neururer S, Mellmann A, Karch H, Orth D, Würzner R. Do complement factor H 402Y and C7 M allotypes predispose to (typical) haemolytic uraemic syndrome? Int J Immunogenet. 2011;38(5):383-387. doi: 10.1111/j.1744-313X.2011.01017.x. Epub 2011 Jun 7.

Frank C, Faber MS, Askar M. et al. Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011. Euro Surveill. 2011;16(21):P.19878.

Vidal JE, Canizález-Román A, Gutiérrez-Jiménez J, Navarro-García F. Molecular pathogenesis, epidemiology and diagnosis of enteropathogenic Escherichia coli. Salud Publica Mex. 2007;49(5):376-386.

Ochoa TJ, Barletta F, Contreras C, Mercado E. New insights into the epidemiology of enteropathogenic Escherichia coli infection. Trans R Soc Trop Med Hyg. 2008;102(9):852-856.

Hill WE, Suhalim R, Richter HC. et al. Polymerase Chain Reaction Screening for Salmonella and Enterohemorrhagic Escherichia coli on Beef Products in Processing Establishments. Foodborne Pathog Dis. 2011;8(9):1045-1053.

Perry LL, SanMiguel P, Minocha U, et al. Sequence analysis of Escherichia coli O157:H7 bacteriophage PhiV10 and identification of a phage-encoded immunity protein that modifies the O157 antigen. FEMS Microbiol Lett. 2009;292(2):182-186.

Kozub-Witkowski E, Krause G, Frankel G. et al. Serotypes and virutypes of enteropathogenic and enterohaemorrhagic Escherichia coli strains from stool samples of children with diarrhoea in Germany. J Appl Microbiol. 2008;104(2):403-410.

Bielaszewska M, Middendorf B, Köck R. et al. Shiga toxin-negative attaching and effacing Escherichia coli: distinct clinical associations with bacterial phylogeny and virulence traits and inferred in-host pathogen evolution. Clin. Infect. Dis. 2008;47(2):208-217.

Askar M, Faber M, Frank C. et al. Update on the ongoing outbreak of haemolytic uraemic syndrome due to Shiga toxin-producing Escherichia coli (STEC) serotype O104, Germany, May 2011. Euro Surveill. 2011;16(22):19883.

Copyright (c) 2016 ACTUAL INFECTOLOGY

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.


© Publishing House Zaslavsky, 1997-2020


   Seo анализ сайта