Lyme Borreliosis: Diagnosis and Treatment Issues
DOI:
https://doi.org/10.22141/2312-413x.2.03.2014.82346Abstract
Lyme borreliosis (LB) — the most common natural focal transmissible infection which occur in the USA, Europe, including Ukraine. It is a multisystem disease affecting the skin, heart, nervous system, joints that are prone to prolonged course. Official registration of the disease in Ukraine is being carried out since 2000. Level of epidemiological registration increases every year: LB incidence in Ukraine since 2000 for 10 years has increased 29 times, in the Dnipropetrovsk region — 12 times. The disease goes through several stages: from the appearance of the primary form — erythema migrans to the formation of chronic forms, which can lead to disability. In 25–50 % of patients, in the absence of adequate antibiotic therapy, in the early LB period we defined chronic form of the disease, especially heart failure. In this paper we present an algorithm for early diagnosis of «minor», clinically silent forms of heart disorders in LB at the early stages of the disease with the aim of rational choice of antibiotic therapy. It is shown that serological markers of LB (antibodies to IgM and IgG Borrelias) can not be used to monitor the effectiveness of therapy.References
Ананьева Л.П. Лайм-боррелиоз или иксодовые клещевые боррелиозы. Этиология, клиника, диагностика // Инфекции и антимикробная терапия. — Институт ревматологии РАМН. — М., 2012. — Ресурс: www.medicusamicus.com
Рева Ю.А. Болезнь Лайма. Как предупредить заражение? / Інформаційне сповіщення лікаря епідеміолога відділу особливо небезпечних інфекцій Дніпропетровської обласної санепідстанції. — Ресурс: http://www.viaduk.net
Лобзин Ю.В., Усков А.Н., Козлов С.С. Лайм-боррелиоз (иксодовые клещевые боррелиозы) // Актуальные инфекции. — СПб.: Фолиант, 2000. — 160 с.
Методичні рекомендації з епідеміології, діагностики та профілактики іксодового кліщового бореліозу (хвороби Лайма) в Україні: наказ МОЗ України від 16.05.2005 № 218. — Ресурс: http://www.moz.gov.ua
Заволока А.А., Заволока Ан.А. Анализ проявления болезни Лайма в Харьковской области, Украина: сб. науч. статей Харьковского зоопарка. — 2010. — Вып. 5. — С. 357-361. — Ресурс: http://animals.kharkov.ua/node/416.
Иксодовые клещевые боррелиозы (болезнь Лайма) у собак: Автореф. дис... канд. биол. наук / Н.С. Пустовит. — М., 2003. — 25 с.
Downloads
Published
Issue
Section
License
Copyright (c) 2016 ACTUAL INFECTOLOGY

This work is licensed under a Creative Commons Attribution 4.0 International License.
Our edition uses the copyright terms of Creative Commons for open access journals.
Authors, who are published in this journal, agree with the following terms:
- The authors retain rights for authorship of their article and grant to the edition the right of first publication of the article on a Creative Commons Attribution 4.0 International License, which allows others to freely distribute the published article, with the obligatory reference to the authors of original works and original publication in this journal.
- Directing the article for the publication to the editorial board (publisher), the author agrees with transmitting of rights for the protection and using the article, including parts of the article, which are protected by the copyrights, such as the author’s photo, pictures, charts, tables, etc., including the reproduction in the media and the Internet; for distributing; for the translation of the manuscript in all languages; for export and import of the publications copies of the writers’ article to spread, bringing to the general information.
- The rights mentioned above authors transfer to the edition (publisher) for the unlimited period of validity and on the territory of all countries of the world.
- The authors guarantee that they have exclusive rights for using of the article, which they have sent to the edition (publisher). The edition (the publisher) is not responsible for the violation of given guarantees by the authors to the third parties.
- The authors have the right to conclude separate supplement agreements that relate to non-exclusive distribution of their article in the form in which it had been published in the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
- The policy of the journal permits and encourages the publication of the article in the Internet (in institutional repository or on a personal website) by the authors, because it contributes to productive scientific discussion and a positive effect on efficiency and dynamics of the citation of the article.
- The rights to the article are deemed transferred by the authors to the edition (the publisher) since the moment of the publication of the article in the printed or electronic version of journal.