Modern clinical and laboratory features of influenza in adults

Authors

  • О.К. Duda Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
  • V.О. Boyko Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
  • L.P. Kotsyubaylo Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
  • A.R. Vega Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2312-413x.5.5.2017.121637

Keywords:

influenza A (H1N1), clinical analysis, pneumonia, acute respiratory distress syndrome, adults, diagnosis, treatment, mortality

Abstract

We examined and treated 472 patients with influenza, 72 of them had radiologically confirmed pneumonia, and 69 were hospitalized in the intensive care unit of Kyiv Municipal Clinical Hospital N 4. We analyzed clinical and laboratory pattern of flu in adults caused by influenza A virus (H1N1). Pneumonia is one of the most frequent complications of influenza, which significantly affects the prognosis. It was shown that unfavorable prognostic criteria are: late medical help (day 5–6 of the disease), the development of acute respiratory distress syndrome, increased white blood cell count and the presence of severe comorbidity.

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References

Pérez-Carrasco M, Lagunes L, Antón A, et al. Influenza infection in the intensive care unit: Four years after the 2009 pandemic. Enferm Infecc Microbiol Clin. 2016 Mar;34(3):177-83. doi: 10.1016/j.eimc.2015.04.004.

Human infection with new influenza A (H1N1) virus: clinical observations from a school associated outbreak in Kobe, Japan, May 2009. Wkly Epidemiol Rec. 2009 Jun 12;84(24):237-44. PMID: 19522091.

Piralla A, Moreno A, Orlandi M, et al. Swine Influenza A(H3N2) Virus Infection in Immunocompromised Man, Italy, 2014. Emerg Infect Dis. 2015 Jul;21(7):1189-91. doi: 10.3201/eid2107.140981.

Smith JR, Ariano RE, Toovey S. The use of antiviral agents for the management of severe influenza. Crit Care Med. 2010 Apr;38(4 Suppl):e43-51. doi: 10.1097/CCM.0b013e3181c85229.

Taubenberger JK, Morens DM. Influenza viruses: breaking all the rules. MBio. 2013 Jul 16;4(4). pii: e00365-13. doi: 10.1128/mBio.00365-13.

Duda OK, Bojko VO, Kocjubajlo LP. Clinical and laboratory features of influenza in adult patients in the epidemic season 2015-2016. Zdorov`a suspil`stva. 2016;5(3-4):20-24. (in Ukrainian).

Kramariov SO, Yevtushenko VV. Approaches to Antibiotic Therapy of Acute Respiratory Infections in Children. Aktual'naya Infektologiya. 2015;1(6):7-12. (in Ukrainian).

Feshchenko YuI, Golubovska OA, Goncharov KA, et al. Community-acquired pneumonia in adults: etiology, pathogenesis, classification, diagnosis, antibiotic therapy (draft clinical guidelines). Part I. Ukrai'ns'kyj pul'monologichnyj zhurnal Український пульмонологічний журн. 2012;4:5-17. (in Ukrainian). Аналогично п.6

Ministry of health of Ukraine. Order № 128 dated March 19, 2007. On the approval of clinical protocols for the provision of medical care in the specialty "Pulmonology". Available from: http://www.moz.gov.ua/ua/portal/dn_20070319_128.html. Accessed: March 19, 2007. (in Ukrainian).

Unified clinical protocol of primary health care for adults and children. Acute respiratory infections (ARVI). In: Ministry of health of Ukraine. Order № 499 dated July 16, 2014. On the approval and implementation of medical and technological documents on the standardization of medical care for influenza and acute respiratory infections. Available from: http://moz.gov.ua/ua/portal/dn_20140716_0499.html. Accessed: July 16, 2014. (in Ukrainian).

Published

2022-01-25

How to Cite

Duda О., Boyko, V., Kotsyubaylo, L., & Vega, A. (2022). Modern clinical and laboratory features of influenza in adults. ACTUAL INFECTOLOGY, 5(5), 239–242. https://doi.org/10.22141/2312-413x.5.5.2017.121637

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Section

Original Researches

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