Monitoring of resistance of bacterial microflora to antibacterial drugs in children with acute respiratory infections


  • Kh.V. Melnyk Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine
  • G.B. Mateyko Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine



acute respiratory infections, bacterial microflora, children, oropharynx, resistance to antibiotics


The article describes the problem of antibiotic resistance of main bacterial pathogens in children with acute respiratory diseases, mechanisms of occurrence and ways to overcome them. The state of antibiotic resistance of pathogenic bacterial microflora of oropharynx was studied in children with acute respiratory infections. The authors emphasize the need for an integrated approach to solving the problem of antibiotic resistance, which includes obligatory systematic monitoring of microbial resistance to antibiotics, educational programs to prevent the misuse of antibiotics as the main factor that provokes the spread of bacterial microflora resistance to antibacterial drugs.


Download data is not yet available.


Kramariov SO, Yevtushenko VV. Approaches to antibiotic therapy of acute respiratory infections in children. Aktualʹnaâ Infektologiâ. 2015;(6):7-12. doi: 10.22141/2312-413x.1.06.2015.78420. (in Ukrainian).

Ministry of Нealth of Ukraine. Order № 499 dated July 16, 2014. On approval and implementation of medical and technological documents on the standardization of medical care for influenza and acute respiratory infections. Available from: Accessed: July 16, 2014. (in Ukrainian).

Lieberthal AS, Carroll AE, Chonmaitree T, et al. The diagnosis and management of acute otitis media. Pediatrics. 2013 Mar;131(3):e964-99. doi: 10.1542/peds.2012-3488.

Shulman ST, Bisno AL, Clegg HW, et al. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis. 2012 Nov 15;55(10):1279-82. doi: 10.1093/cid/cis847.

Simoes EAF, Cherian T, Chow J, Shahid-Salles SA, Laxminarayan R, John TJ. Acute Respiratory Infections in Children. In: Jamison DT, Breman JG, Measham AR, et al., editors. Disease Control Priorities in Developing Countries. 2nd ed. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; New York: Oxford University Press; 2006. 483-498 pp.

Duka KD, Ilchenko SI, Koreniuk OS, Degtiar SP, Fomenkova NV. Current issues of antibiotic use for acute infections treatment in children. Zdorovʹe rebenka. 2015;(68):9-12. doi: 10.22141/2224-0551.8.68.2015.75133. (in Ukrainian).

Kramarev SA. Treatment of influenza and acute respiratory viral infections in children. Racionalʹna farmakoterapia. 2008;(3-2):24-28. (in Russian).

Svistushkin VM, Nikiforova GN, Vlasova NP. Treatment options for patients with acute respiratory viral infections at present time. Lechaschii Vrach. 2013;(1):34-36. (in Russian).

Abaturov AE, Agafonovf EA, Gerasimenko OM, et al. Initial antibacterial therapy of community-acquired forms of pneumonia in children. Sovremennaya pediatriya. 2011;(38):95-98. (in Russian).

Krjuchko TO, Tkachenko OJa. Ways of overcoming antibiotic resistance in pediatrics. Zdorovʹe rebenka. 2012;(36):135. (in Ukrainian).

Feshchenko YuI, Gumenuk MI, Denisov OS. Antibiotic resistance of microorganisms. State of problem and way of decision. Ukraïnsʹkij himioterapevticnij zurnal. 2010;(23):4-7. (in Ukrainian).

Belousov IuB. Klinicheskaia farmakologiia i farmakoterapiia [Clinical Pharmacology and Pharmacotherapy]. 3rd ed. Moscow: MIA; 2010. 872 p. (in Russian).

Volyanska LA, Romanyuk LB. Rational treatment of acute respiratory infections in children is a decrease of menace of antibiotic resistance. Zdorovʹe rebenka. 2011;(32):43-46. (in Ukrainian).

Dziublyk YaO. Antibiotic resistance of respiratory infections pathogens: a review of soar study results and the perspectives of microbiological monitoring in Ukraine. Ukraïnsʹkij pulʹmonologicnij zurnal. 2010;(4):33-35. (in Ukrainian).



How to Cite

Melnyk, K., & Mateyko, G. (2021). Monitoring of resistance of bacterial microflora to antibacterial drugs in children with acute respiratory infections. ACTUAL INFECTOLOGY, 6(5), 230–233.



Original Researches