Evaluation of the effectiveness of the treatment of intestinal ascariasis in children

Authors

  • T.V. Sorokman HSEI “Bukovinian State Medical University”, Chernivtsi, Ukraine
  • P.M. Moldovan HSEI “Bukovinian State Medical University”, Chernivtsi, Ukraine

DOI:

https://doi.org/10.22141/2312-413x.7.5.2019.183706

Keywords:

ascariasis, children, Vormil Fito

Abstract

Background. Parasitic diseases remain one of the most common types of pathology in the XXI century and are a medical and social problem. Of the identified helminths, 90 % of cases occur in the pediatric population. Ascariasis and enterobiasis are the most common. A comprehensive approach to the correction of disorders caused by both the use of anthelmintic drugs and the presence of helminths in the body. The purpose was to evaluate the effectiveness of complex treatment of intestinal ascariasis in children. Materials and methods. The work is based on the results of a survey of 178 children aged 3 to 18 years with intestinal form of ascariasis. Ascariasis was diagnosed using coprological survey and the Parasep concentration method. The examined children were divided into two groups: group I (n = 99) received albendazole (200–400 mg per day) in the complex treatment of ascariasis (antihistamine, sorbent, pro­biotic); group II (n = 80) received Vormil Fito in addition to the standard scheme. Results. The average duration of pain relief in children was 3.6 ± 0.2 and 2.6 ± 0.9 days in comparison group and in the basic group, respectively, p < 0.001. The dyspeptic syndrome signs were reduced within 5.3 ± 0.3 and 4.3 ± 0.2 days in the comparison group and in the basic group, respectively, p < 0.01. The signs of asthenovegetative syndrome in children of the comparison group were eliminated within 8–10 days, while for the children of the basic group — within 6–7 days. The use of complex treatment of children allowed reducing the time of pain relief by 27.8 %, dyspeptic and asthenovegetative syndromes by 14.0 and 25.0 %, respectively. Clinical recovery in children treated with the proposed method was faster, on average by 1.8 times, compared to the treatment with abendazole (Vormil) only. The parasitological efficacy of the proposed method is 95 %, whereas the use of albendazole (Vormil) alone is 89.8 %. Conclusions. Adding the phytocomplex of Vormil Fito to the scheme of treatment of patients with ascariasis accelerates the recovery of patients, quickly improves their well­being, provides high clinical and anti­parasitic efficacy.

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References

Gras-Ozimek J, Ozimek W, Kozińska U [et al]. Ascariasis and its relationship with selected psycho-neurological symptoms among children and adults in Poland. Pol Merkur Lekarski. 2019 Apr 29;46(274):165-171.

Zakzuk J, Casadiego S, Mercado A, Alvis-Guzman N, Caraballo L. Ascaris lumbricoides infection induces both, reduction and increase of asthma symptoms in a rural community. Acta Trop. 2018 Nov;187:1-4. doi: 10.1016/j.actatropica.2018.07.016.

Multicriteria-Based Ranking for Risk Management of Food-Borne Parasites. Microbiological Risk Assessment Series (MRA) 23. FAO/WHO, 2014:287 р.

Maidannyk VH. Helminthiasis in children: an urgent problem in the practice of a pediatrician. 2010;3(24):35-37.

Data Tough choices : investing in health for development. Delhi: World Bank, 2006.122p.

Zakharchuk OI, Pishak VP, Kryvchanska MI, Myroniuk MB. Prevalence of some worms in Chernivtsi region. Infektsiini khvoroby. 2015;№ 2:67-72.

Kryvopustov SP, Shcherbynskaia EM, Lohynova EA [et al.]. Helminthiasis in clinical pediatrics: issues of diagnosis, therapy, prevention. Na dopomohu pediatru. 2011;№4 (31):71–75.

Bodnia KI, Marchenko VH, Yefimenko TP, Kholtobina LV. Scheme of examination of patients with parasitosis by clinical indicators in the practice of a family doctor. Metodychni rekomendatsii. Kh.: KhMAPO, 2005: 24 s.

Ershova YB, Mochalova AA, Cherkasova SN, Chernova EV. Parasitic infestations in the practice of a pediatrician. Zdorove rebenka. 2007; № 2(5):44.

Bodnia EY. Helminthiasis: a modern view of therapy. Novosty medytsynы y farmatsyy. 2017; № 9(621):14-17.

Published

2021-09-28

How to Cite

Sorokman, T., & Moldovan, P. (2021). Evaluation of the effectiveness of the treatment of intestinal ascariasis in children. ACTUAL INFECTOLOGY, 7(5), 264–268. https://doi.org/10.22141/2312-413x.7.5.2019.183706

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Original Researches

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